01 - Generously season beef chunks with salt and pepper on all sides.
02 - Heat olive oil in a large skillet over medium-high heat. Sear beef chunks for 2-3 minutes per side until deeply browned. Transfer to slow cooker.
03 - Add onion, carrots, and celery to the same skillet. Cook 4-5 minutes until softened. Stir in garlic and tomato paste; cook 1 minute until fragrant.
04 - Transfer vegetables to slow cooker with beef. Add crushed tomatoes, red wine, beef broth, oregano, thyme, bay leaves, and red pepper flakes. Stir to combine.
05 - Cover and cook on low for 8 hours until beef is fork-tender and easily shreds. Remove and discard bay leaves.
06 - Shred beef directly in slow cooker using two forks. Stir thoroughly to incorporate meat into sauce. Taste and adjust seasoning with salt and pepper as needed.
07 - Twenty minutes before serving, cook pappardelle according to package directions. Drain, reserving 1/2 cup pasta water.
08 - Toss cooked pappardelle with beef ragu, adding splashes of reserved pasta water as needed to coat noodles evenly. Serve hot with additional Parmesan and fresh parsley sprinkled on top.