01 - Pat tilapia fillets dry with paper towels. Combine chili powder, cumin, smoked paprika, garlic powder, salt, and black pepper in a small bowl. Season both sides of tilapia generously with spice mixture. Drizzle with olive oil and lime juice, turning to coat evenly.
02 - Heat a large nonstick skillet over medium-high heat. Add seasoned fillets and cook for 3-4 minutes per side until golden brown and fish flakes easily with a fork. Remove from heat and let rest 2 minutes. Flake into bite-sized pieces using a fork.
03 - Combine shredded cabbage, carrots, and chopped cilantro in a large bowl. Add lime juice and olive oil. Season with salt and pepper to taste. Toss thoroughly until vegetables are evenly coated.
04 - Whisk together sour cream (or Greek yogurt), lime juice, hot sauce if desired, and salt in a small bowl until smooth and fully combined. Adjust seasoning to taste.
05 - Heat tortillas in a dry skillet over medium heat for 30 seconds per side until warm and pliable, or microwave between damp paper towels for 20-30 seconds. Keep warm until ready to serve.
06 - Layer a generous portion of slaw onto each warm tortilla, followed by seasoned tilapia pieces. Drizzle with crema. Top with sliced avocado, fresh cilantro leaves, and a squeeze of fresh lime juice.
07 - Arrange tacos on a serving platter with extra lime wedges on the side. Serve while tortillas are warm and fish is at its best temperature.